Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

• Main Authors: Kapil Gadkar (Author), Justin Feigelman (Author), Siddharth Sukumaran (Author), Manoj C. Rodrigo (Author), Tracy Staton (Author), Fang Cai (Author), Rebecca N. Bauer (Author), David F. Choy (Author), Cynthia L. Stokes (Author), Heleen Scheerens (Author), Saroja Ramanujan (Author)
• Format: Book
• Published: Wiley, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Asthma is a complex, heterogeneous disease with a high unmet medical need, despite therapies targeting a multitude of pathways. The ability to quantitatively integrate preclinical and clinical data on these pathways could aid in the development and testing of novel targets and therapeutics....