Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration
Messenger RNA (mRNA) has generated great attention due to its broad potential therapeutic applications, including vaccines, protein replacement therapy, and immunotherapy. Compared to other nucleic acids (e.g., siRNA and pDNA), there are more opportunities to improve the delivery efficacy of mRNA th...
Saved in:
Main Authors: | Xueliang Yu (Author), Shuai Liu (Author), Qiang Cheng (Author), Sang M. Lee (Author), Tuo Wei (Author), Di Zhang (Author), Lukas Farbiak (Author), Lindsay T. Johnson (Author), Xu Wang (Author), Daniel John Siegwart (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Preparation of poly(aluminium chloride) and poly(aluminium silicate chloride) from sludge of C₅ resin
by: Sookhasart Jareronpol
Published: (2013) -
Design of Non-Haemolytic Nanoemulsions for Intravenous Administration of Hydrophobic APIs
by: Line Séguy, et al.
Published: (2020) -
Enhancing hydrophobicity of electrospun poly(vinyl alcohol) fibers by chemical reaction of hydroxyl groups
by: Navarun Chaim-Ngoen
Published: (2014) -
Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain
by: Julia F Alterman, et al.
Published: (2015) -
Mutual Effects of Hydrogen Bonding and Polymer Hydrophobicity on Ibuprofen Crystal Inhibition in Solid Dispersions with Poly(<i>N</i>-vinyl pyrrolidone) and Poly(2-oxazolines)
by: Xiaoning Shan, et al.
Published: (2021)