Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

• Main Authors: Marine L. Croze (Author), Marcus F. Flisher (Author), Arthur Guillaume (Author), Caroline Tremblay (Author), Glyn M. Noguchi (Author), Sabrina Granziera (Author), Kevin Vivot (Author), Vincent C. Castillo (Author), Scott A. Campbell (Author), Julien Ghislain (Author), Mark O. Huising (Author), Vincent Poitout (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor whose activation in islets of Langerhans promotes insulin and glucagon secretion and inhibits soma...