Release of HMGB1 in Podocytes Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury

Objective. Acute kidney injury (AKI) usually occurs during sepsis. Inflammation factors, such as high-mobility group box 1 (HMGB1), are dramatically upregulated under septic conditions. In our current work, the functions of HMGB1 in AKI were explored. Methods. An AKI model was induced by the lipopol...

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Main Authors: Zhao Gao (Author), Li Lu (Author), Xinghua Chen (Author)
Format: Book
Published: Hindawi Limited, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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