The landscape of expression and alternative splicing variation across human traits

• Main Authors: Raquel García-Pérez (Author), Jose Miguel Ramirez (Author), Aida Ripoll-Cladellas (Author), Ruben Chazarra-Gil (Author), Winona Oliveros (Author), Oleksandra Soldatkina (Author), Mattia Bosio (Author), Paul Joris Rognon (Author), Salvador Capella-Gutierrez (Author), Miquel Calvo (Author), Ferran Reverter (Author), Roderic Guigó (Author), François Aguet (Author), Pedro G. Ferreira (Author), Kristin G. Ardlie (Author), Marta Melé (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Understanding the consequences of individual transcriptome variation is fundamental to deciphering human biology and disease. We implement a statistical framework to quantify the contributions of 21 individual traits as drivers of gene expression and alternative splicing variation across 46...