Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi.

• Main Authors: Raphael Souza Pavani (Author), Marcelo Santos da Silva (Author), Carlos Alexandre Henrique Fernandes (Author), Flavia Souza Morini (Author), Christiane Bezerra Araujo (Author), Marcos Roberto de Mattos Fontes (Author), Osvaldo Augusto Sant'Anna (Author), Carlos Renato Machado (Author), Maria Isabel Cano (Author), Stenio Perdigão Fragoso (Author), Maria Carolina Elias (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Replication Protein A (RPA), the major single stranded DNA binding protein in eukaryotes, is composed of three subunits and is a fundamental player in DNA metabolism, participating in replication, transcription, repair, and the DNA damage response. In human pathogenic trypanosomatids, only limited s...