Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population

• Asıl Yazarlar: Satomi Mitsuhashi (Yazar), Martin C. Frith (Yazar), Naomichi Matsumoto (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Tandem repeats are highly mutable and contribute to the development of human disease by a variety of mechanisms. It is difficult to predict which tandem repeats may cause a disease. One hypothesis is that changeable tandem repeats are the source of genetic diseases, because disea...