Reduced variability in tacrolimus pharmacokinetics following intramuscular injection compared to oral administration in cynomolgus monkeys: Investigating optimal dosing regimens

• Үндсэн зохиолчид: Kyo Won Lee (Зохиогч), Tae Hwan Kim (Зохиогч), Jong Bong Lee (Зохиогч), Kyeong Sik Kim (Зохиогч), Jae Berm Park (Зохиогч), Pavel Gershkovich (Зохиогч), Sun Dong Yoo (Зохиогч), Soyoung Shin (Зохиогч), Beom Soo Shin (Зохиогч), Sung Joo Kim (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2019-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Tacrolimus is one of the most commonly used immunosuppressive agents in animal models of transplantation. However, in these models, oral administration is often problematic due to the lowered compliance associated with highly invasive surgery and due to malabsorption in the intestinal tract. Therefo...