The abrupt pathological deterioration of cisplatin‐induced acute kidney injury: Emerging of a critical time point

• Egile Nagusiak: Qin Gong (Egilea), Mulan Wang (Egilea), Ya Jiang (Egilea), Chengliang Zha (Egilea), Dong Yu (Egilea), Fan Lei (Egilea), Yingying Luo (Egilea), Yulin Feng (Egilea), Shilin Yang (Egilea), Jun Li (Egilea), Lijun Du (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2021-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Cisplatin (CP), an anticancer drug, often causes kidney damage. However, the mechanism of CP‐induced acute kidney injury (AKI) is not completely understood. AKI was induced by intravenous injection (i.v.) of cisplatin at doses of 5, 8, and 10 mg/kg. Anemoside B4 (B4) (20 mg/kg, i.m.) and de...