Multitargeted Virtual Screening and Molecular Simulation of Natural Product-like Compounds against GSK3β, NMDA-Receptor, and BACE-1 for the Management of Alzheimer's Disease

• Main Authors: Danish Iqbal (Author), Md Tabish Rehman (Author), Mohamed F. Alajmi (Author), Mohammed Alsaweed (Author), Qazi Mohammad Sajid Jamal (Author), Sharifa M. Alasiry (Author), Awatif B. Albaker (Author), Munerah Hamed (Author), Mehnaz Kamal (Author), Hind Muteb Albadrani (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The complexity of Alzheimer's disease (AD) and several side effects of currently available medication inclined us to search for a novel natural cure by targeting multiple key regulatory proteins. We initially virtually screened the natural product-like compounds against GSK3β, NMDA receptor, an...