A human <it>MYBPC3</it> mutation appearing about 10 centuries ago results in a hypertrophic cardiomyopathy with delayed onset, moderate evolution but with a risk of sudden death

• Main Authors: Teirlinck Carolien H (Author), Senni Faïza (Author), Malti Rajae El (Author), Majoor-Krakauer Danielle (Author), Fellmann Florence (Author), Millat Gilles (Author), André-Fouët Xavier (Author), Pernot François (Author), Stumpf Michaël (Author), Boutarin Jean (Author), Bouvagnet Patrice (Author)
• Format: Book
• Published: BMC, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hypertrophic Cardiomyopathy (HCM) is a genetically heterogeneous disease. One specific mutation in the <it>MYBPC3</it> gene is highly prevalent in center east of France giving an opportunity to define the clinical profile...