Parkin and its molecular associations in gliomas - a systematic review

• Main Authors: Eduardo Morais de Castro (Author), Leonardo Vinícius Barbosa (Author), João Vitor Alves Ferreira (Author), Diancarlos Pereira de Andrade (Author), Rosiane Guetter Mello (Author), Luiz Fernando Bleggi Torres (Author), Lucia de Noronha (Author), Cleber Machado-Souza (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Parkin, a protein encoded by PRKN, discovered in the context of Parkinson's disease, controls proteasomal degradation by protein ubiquitination and acts on cell cycle control and mitochondrial homeostasis, among other cellular processes. Parkin has been also implicated in several carci...