Oral Vancomycin Prophylaxis for Primary and Secondary Prevention of <i>Clostridioides difficile</i> Infection in Patients Treated with Systemic Antibiotic Therapy: A Systematic Review, Meta-Analysis and Trial Sequential Analysis

• Main Authors: Alberto Enrico Maraolo (Author), Maria Mazzitelli (Author), Emanuela Zappulo (Author), Riccardo Scotto (Author), Guido Granata (Author), Roberto Andini (Author), Emanuele Durante-Mangoni (Author), Nicola Petrosillo (Author), Ivan Gentile (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: <i>Clostridioides difficile</i> infection (CDI) is associated with substantial morbidity and mortality as well as high propensity of recurrence. Systemic antibiotic therapy (SAT) represents the top inciting factor of CDI, both primary and recurrent (rCDI). Among the many stra...