Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

• Main Authors: Paola Oliva (Author), Romeo Romagnoli (Author), Barbara Cacciari (Author), Stefano Manfredini (Author), Chiara Padroni (Author), Andrea Brancale (Author), Salvatore Ferla (Author), Ernest Hamel (Author), Diana Corallo (Author), Sanja Aveic (Author), Noemi Milan (Author), Elena Mariotto (Author), Giampietro Viola (Author), Roberta Bortolozzi (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two different series of fifty-two compounds, based on 3',4',5'-trimethoxyaniline (<b>7a-ad</b>) and variably substituted anilines (<b>8a-v</b>) at the 7-position of the 2-substituted-[1,2,4]triazolo [1,5-<i>a</i>]pyrimidine nucleus, had moderate to...