Topical application of green tea polyphenol (−) epigallocatechin-3-gallate for prevention of recurrent oral neoplastic lesions

• Main Authors: Angela J Yoon (Author), Jing Shen (Author), Regina M Santella (Author), Elizabeth M Philipone (Author), Hui-Chen Wu (Author), Sidney B Eisig (Author), Andrew Blitzer (Author), Lanny G Close (Author), David J Zegarelli (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: A preliminary study was conducted to investigate the feasibility of using an oral cancer chemopreventive agent (−)-epigallocatechin-3-gallate (EGCG), the most biologically active component in the green tea extract, in a form of "swish-and-spit" mouthwash. Such application of EGC...