Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Depriving cancer cells of sufficient NAD levels, mainly through interfering with their NAD-producing capacity, has been conceived as a promising anti-cancer strategy. Numerous inhibitors of the NAD-producing enzyme, nicotinamide phosphoribosyltransferase (NAMPT), have been developed over the past tw...

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主要な著者: Moustafa S. Ghanem (著者), Irene Caffa (著者), Alberto Del Rio (著者), Jorge Franco (著者), Marco Daniele Parenti (著者), Fiammetta Monacelli (著者), Michele Cea (著者), Amr Khalifa (著者), Aimable Nahimana (著者), Michel A. Duchosal (著者), Silvia Ravera (著者), Nadia Bertola (著者), Santina Bruzzone (著者), Alessio Nencioni (著者), Francesco Piacente (著者)
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出版事項: MDPI AG, 2022-07-01T00:00:00Z.
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