Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery
Depriving cancer cells of sufficient NAD levels, mainly through interfering with their NAD-producing capacity, has been conceived as a promising anti-cancer strategy. Numerous inhibitors of the NAD-producing enzyme, nicotinamide phosphoribosyltransferase (NAMPT), have been developed over the past tw...
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MDPI AG,
2022-07-01T00:00:00Z.
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