Dosing Optimization of Posaconazole in Lung-Transplant Recipients Based on Population Pharmacokinetic Model

• Үндсэн зохиолчид: Eliška Dvořáčková (Зохиогч), Martin Šíma (Зохиогч), Andrea Zajacová (Зохиогч), Kristýna Vyskočilová (Зохиогч), Tereza Kotowski (Зохиогч), Kateřina Dunovská (Зохиогч), Eva Klapková (Зохиогч), Jan Havlín (Зохиогч), Robert Lischke (Зохиогч), Ondřej Slanař (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Although posaconazole tablets show relatively low variability in pharmacokinetics (PK), the proportion of patients achieving the PK/PD target at the approved uniform dose for both prophylaxis and therapy is not satisfactory. The aim of this study was to develop a posaconazole population PK model in...