Phosphoinositide 3-kinase: friend and foe in cardiovascular disease
Class I phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases activated by cell membrane receptors, either receptor tyrosine kinases (RTKs) or G protein-coupled receptors (GPCRs), to catalyze the production of the lipid second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3). T...
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Frontiers Media S.A.,
2015-08-01T00:00:00Z.
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