Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens

• Main Authors: Liangliang He (Author), Chunxia Xu (Author), Ziying Wang (Author), Shuyi Duan (Author), Jinjin Xu (Author), Chuan Li (Author), Xinsheng Yao (Author), Frank J. Gonzalez (Author), Zifei Qin (Author), Zhihong Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xian-Ling-Gu-Bao (XLGB) capsule, a well-known traditional Chinese medicine prescription, is widely used for the treatment of osteoporosis. It could significantly increase the levels of estrogen in ovariectomized rats and mice. However, this working mechanism has not been well elucidated. Considering...