Exercise attenuates polyglutamine‐mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy

Exercise attenuates polyglutamine‐mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy

Abstract Background Spinal and bulbar muscular atrophy (SBMA) is a hereditary neuromuscular disorder caused by the expansion of trinucleotide cytosine-adenine-guanine (CAG) repeats, which encodes a polyglutamine (polyQ) tract in the androgen receptor (AR) gene. Recent evidence suggests that, in addi...

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Main Authors: Tomoki Hirunagi (Author), Hideaki Nakatsuji (Author), Kentaro Sahashi (Author), Mikiyasu Yamamoto (Author), Madoka Iida (Author), Genki Tohnai (Author), Naohide Kondo (Author), Shinichiro Yamada (Author), Ayuka Murakami (Author), Seiya Noda (Author), Hiroaki Adachi (Author), Gen Sobue (Author), Masahisa Katsuno (Author)
Format: Book
Published: Wiley, 2024-02-01T00:00:00Z.
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