Mechanistic Models Fit to Ed Data on >40,000 Trout Exposed to Dibenzo[]Pyrene Indicate Mutations Do Not Drive Increased Tumor Risk

• Yazar: Kenneth T. Bogen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: SAGE Publishing, 2014-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

ED 001 -study data on increased liver and stomach tumor risks in >40,000 trout fed dibenzo[ a,l ]pyrene (DBP), one of the most potently mutagenic chemical carcinogens known, provide the greatest low-dose dose-response resolution of any experimentally induced tumor data set to date. Although multi...