Tautomycetin Induces Apoptosis by Inactivating Akt Through a PP1-Independent Signaling Pathway in Human Breast Cancer Cells

• Ngā kaituhi matua: Mingshan Niu (Author), Yan Sun (Author), Xuejiao Liu (Author), Li Tang (Author), Rongguo Qiu (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2013-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Tautomycetin (TMC), originally isolated from Streptomyces griseochromogenes, has been suggested as a potential drug retaining specificity toward colorectal cancer. However, we found that TMC exhibited inhibitory effects on cell proliferation of many cancer cell lines including adriamycin-resistant h...