Pharmacokinetics and safety of highly variable valsartan in single-pill combination with amlodipine versus its generic formulation: a randomized, three-cycle, three-sequence, partially replicated crossover phase I bioequivalence clinical trial

• Asıl Yazarlar: Bo Qiu (Yazar), Haojing Song (Yazar), Congyang Ding (Yazar), Xue Sun (Yazar), Runxuan Du (Yazar), Haotian Yang (Yazar), Wanjun Bai (Yazar), Zhanjun Dong (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Valsartan/amlodipine (I) is a single-pill combination (SPC) of an angiotensin II receptor blocker (ARB) and a calcium channel blocker (CCB) for treating hypertension. A clinical trial was performed to demonstrate that the test and reference valsartan/amlodipine formulations were bioequivalent under...