Dexmedetomidine Attenuates Ferroptosis-Mediated Renal Ischemia/Reperfusion Injury and Inflammation by Inhibiting ACSL4 via α2-AR

• Autors principals: Wen-hui Tao (Autor), Xi-sheng Shan (Autor), Jia-xin Zhang (Autor), Hua-yue Liu (Autor), Bi-ying Wang (Autor), Xiang Wei (Autor), Mian Zhang (Autor), Ke Peng (Autor), Jun Ding (Autor), Shang-xian Xu (Autor), Lin-gui Li (Autor), Jun-kai Hu (Autor), Xiao-wen Meng (Autor), Fu-hai Ji (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Ischemia-reperfusion (I/R) injury is a serious clinical pathology associated with acute kidney injury (AKI). Ferroptosis is non-apoptotic cell death that is known to contribute to renal I/R injury. Dexmedetomidine (Dex) has been shown to exert anti-inflammatory and organ protective effects. This stu...