Methods of acute biological assays in guinea-pigs for the study of toxicity and innocuity of drugs and chemicals

• Autori principali: Gui Mi Ko (Autore), Adela Rosenkranz (Autore), Clélia Rejane Antonio Bertoncini (Autore), Neide Hyppolito Jurkiewicz (Autore), Mirian Ghiraldini Franco (Autore), Aron Jurkiewicz (Autore)
• Natura: Libro
• Pubblicazione: Universidade de São Paulo, 2010-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

In this study, 602 samples were tested by the following assays performed at the animal facilities (Cedeme) of the Federal University of São Paulo (UNIFESP): 385 for dermal irritability, 90 for ocular irritability (discontinued in 1995), 31 for systemic toxicity by injection, 26 for oral acute toxici...