Computational Models on Pathological Redox Signalling Driven by Pregnancy: A Review

• Main Authors: Samprikta Manna (Author), Camino S. M. Ruano (Author), Jana-Charlotte Hegenbarth (Author), Daniel Vaiman (Author), Shailendra Gupta (Author), Fergus P. McCarthy (Author), Céline Méhats (Author), Cathal McCarthy (Author), Clara Apicella (Author), Julia Scheel (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is associated with a myriad of diseases including pregnancy pathologies with long-term cardiovascular repercussions for both the mother and baby. Aberrant redox signalling coupled with deficient antioxidant defence leads to chronic molecular impairment. Abnormal placentation has bee...