Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection

• Main Authors: Jacob Raiten (Author), Genevieve M. Abd (Author), Shane B. Handelsman (Author), Harshank V. Patel (Author), Jennifer C. Ku (Author), Agata M. Parsons (Author), Jonathan L. Wassink (Author), Sheridan L. Hayes (Author), Juliana Overbay (Author), Yong Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stem cell therapy has shown immense promise in treating genetic disorders, particularly muscular diseases like Duchenne muscular dystrophy (DMD). This study investigates a novel method to enhance the viability of stem cell transplants in DMD by upregulating Programmed Death Ligand 1 (PD-L1) in muscl...