Chiral Analysis of the Key Intermediates of Tenofovir Alafenamide Fumarate

(R)-Tenofovir phenyl ester ((R)-1) and (R)-tenofovir diphenyl ester ((R)-2) are key intermediates for the practical synthesis of tenofovir alafenamide fumarate, which is a mainstay antiretroviral for the treatment of chronic hepatitis B and HIV-1 infections. This article deals with the chiral analys...

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Main Authors: Man Li (Author), Ting Zhou (Author), Qing-Wen Zhang (Author)
Format: Book
Published: Georg Thieme Verlag KG, 2023-03-01T00:00:00Z.
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