pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy

• Main Authors: Silvia Tampucci (Author), Lorenzo Guazzelli (Author), Susi Burgalassi (Author), Sara Carpi (Author), Patrizia Chetoni (Author), Andrea Mezzetta (Author), Paola Nieri (Author), Beatrice Polini (Author), Christian Silvio Pomelli (Author), Eleonora Terreni (Author), Daniela Monti (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to selectively release the drug in the tumor acidic microenvironment represents a reliable option for targeted delivery. In this context, a series of newly synthesized surface-active fatty acid-protic ionic liquids (...