Profiling Docetaxel in Plasma and Urine Samples from a Pediatric Cancer Patient Using Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction Combined with LC-MS/MS

• मुख्य लेखकों: Olga Maliszewska (लेखक), Anna Roszkowska (लेखक), Marcin Lipiński (लेखक), Natalia Treder (लेखक), Ilona Olędzka (लेखक), Piotr Kowalski (लेखक), Tomasz Bączek (लेखक), Ewa Bień (लेखक), Małgorzata Anna Krawczyk (लेखक), Alina Plenis (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In recent years, therapeutic drug monitoring (TDM) has been applied in docetaxel (DOC)-based anticancer therapy to precisely control various pharmacokinetic parameters, including the concentration of DOC in biofluids (e.g., plasma or urine), its clearance, and its area under the curve (AUC). The abi...