Formulation and evaluation of docetaxel nanosuspensions: In-vitro evaluation and cytotoxicity

• Main Authors: Mohamed A. Ibrahim (Author), Gamal A. Shazly (Author), Fadilah S. Aleanizy (Author), Fulwah Y. Alqahtani (Author), Gehan M. Elosaily (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The aim of the present study was to formulate the anticancer drug; docetaxel (DOX) as nanoparticles to enhance its biological activity. Methodology: Solvent precipitation method was used to prepare DOX-loaded nanoparticles and was stabilized by different concentrations of hydroxypropyl me...