Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis

• Main Authors: Wei Zhao (Author), Huan-Huan Yu (Author), Wei-Wei Meng (Author), Ai-Min Liu (Author), Bu-Xin Zhang (Author), Ying Wang (Author), Jie Li (Author), Li Wang (Author), Yu-Fu Fang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Atopic dermatitis (AD) is a common inflammatory skin disease characterized with hyperactivation of type 2 T helper (Th2) immune responses. Icariin is a flavonoid glucoside with anti-inflammatory activities, which has been used to treat multiple diseases.Objective The present study in...