OPA1-related dominant optic atrophy is not strongly influenced by mitochondrial DNA background

• Main Authors: Amati-Bonneau Patrizia (Author), Thoraval Didier (Author), Murail Pascal (Author), Chevrollier Arnaud (Author), Rocher Christophe (Author), Ferré Marc (Author), Pierron Denis (Author), Reynier Pascal (Author), Letellier Thierry (Author)
• Format: Book
• Published: BMC, 2009-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are the most frequent forms of hereditary optic neuropathies. LHON is associated with mitochondrial DNA (mtDNA) mutations whereas ADOA is mai...