Differential Host Immune Responses after Infection with Wild-Type or Lab-Attenuated Rabies Viruses in Dogs.

• Main Authors: Clement W Gnanadurai (Author), Yang Yang (Author), Ying Huang (Author), Zhenguang Li (Author), Christina M Leyson (Author), Tanya L Cooper (Author), Simon R Platt (Author), Stephen B Harvey (Author), Douglas C Hooper (Author), Milosz Faber (Author), Zhen F Fu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

METHODOLOGY/PRINCIPAL FINDINGS:The experimental infection of dogs with TriGAS induced high levels of VNA in the serum, whereas wt RABV infection did not. Dogs infected with TriGAS developed antibodies against the virus including its glycoprotein, whereas dogs infected with DRV-NG11 only developed ra...