Inflammatory Stress Potentiates Emodin-Induced Liver Injury in Rats

• Egile Nagusiak: Can eTu (Egilea), Dan eGao (Egilea), Xiao-fei eLi (Egilea), Chun-yu eLi (Egilea), Rui-sheng eLi (Egilea), Yan-ling eZhao (Egilea), Na eLi (Egilea), Ge- (Egilea), Jing-yao ePang (Egilea), He-rong eCui (Egilea), Zhi-jie eMa (Egilea), Xiao-he eXiao (Egilea), Jia-Bo eWang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Herbal medicines containing emodin, widely used for the treatment of hepatitis in clinic, have been reported with hepatotoxicity in individuals. A modest inflammatory stress potentiating liver injury has been linked to the idiosyncratic drug-induced liver injury (IDILI). In this study, we investigat...