Inflammatory Stress Potentiates Emodin-Induced Liver Injury in Rats

• Main Authors: Can eTu (Author), Dan eGao (Author), Xiao-fei eLi (Author), Chun-yu eLi (Author), Rui-sheng eLi (Author), Yan-ling eZhao (Author), Na eLi (Author), Ge- (Author), Jing-yao ePang (Author), He-rong eCui (Author), Zhi-jie eMa (Author), Xiao-he eXiao (Author), Jia-Bo eWang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herbal medicines containing emodin, widely used for the treatment of hepatitis in clinic, have been reported with hepatotoxicity in individuals. A modest inflammatory stress potentiating liver injury has been linked to the idiosyncratic drug-induced liver injury (IDILI). In this study, we investigat...