Therapeutic effect of fenofibrate for non-alcoholic steatohepatitis in mouse models is dependent on regime design

• Main Authors: Xinxue Wang (Author), Jia Luo (Author), Zhuoheng Lu (Author), Shenzhe Fang (Author), Mengxia Sun (Author), Wenjing Luo (Author), Jianwei Shen (Author), Aiming Liu (Author), Hua Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver diseases. In most cases, NAFLD progresses from benign steatosis to steatohepatitis (NASH), and then to cirrhosis. No treatment is currently approved for NAFLD/NASH in the clinic. Fenofibrate (FENO) has been c...