Drug-drug interaction between tacrolimus and caspofungin in Chinese kidney transplant patients with different genotypes

• Main Authors: Yundi Zhang (Author), Bowen Shen (Author), Yue Li (Author), Huiying Zong (Author), Xiaoming Zhang (Author), Xiaohong Cao (Author), Fengxi Liu (Author), Yan Li (Author)
• Format: Book
• Published: SAGE Publishing, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The effect of drug-drug interaction between tacrolimus and caspofungin on the pharmacokinetics of tacrolimus in different CYP3A5 genotypes has not been reported in previous studies. Objectives: To investigate the effect of caspofungin on the blood concentration and dose of tacrolimus und...