Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective

• Үндсэн зохиолчид: Naomi Scarano (Зохиогч), Chiara Brullo (Зохиогч), Francesca Musumeci (Зохиогч), Enrico Millo (Зохиогч), Santina Bruzzone (Зохиогч), Silvia Schenone (Зохиогч), Elena Cichero (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Sirtuins (SIRTs) are classified as class III histone deacetylases (HDACs), a family of enzymes that catalyze the removal of acetyl groups from the ε-N-acetyl lysine residues of histone proteins, thus counteracting the activity performed by histone acetyltransferares (HATs). Based on their involvemen...