Detection of MDM2 gene amplification on tissue microarray-based Fluorescence In-Situ Hybridization (FISH) in well-differentiated and dedifferentiated liposarcomas, displaying a wide morphological spectrum: A validation study at a tertiary cancer referral centre

• Hauptverfasser: Bharat Rekhi (Verfasst von), Nupur Karnik (Verfasst von), Radhika Agrawal (Verfasst von), Omshree Shetty (Verfasst von), Shraddha Patkar (Verfasst von)
• Format: Buch
• Veröffentlicht: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background: Liposarcomas including atypical lipomatous tumors (ALT)/well-differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas (DDLPSs) display a histomorphological spectrum with their several diagnostic mimics. Murine double minute 2(MDM2) gene amplification characterizes ALT/WDLPS...