Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD

• Main Authors: Marit Stockfelt (Author), Karin Christenson (Author), Anders Andersson (Author), Lena Björkman (Author), Médea Padra (Author), Bettina Brundin (Author), Koustav Ganguly (Author), Helga Asgeirsdottir (Author), Sara Lindén (Author), Ingemar Qvarfordt (Author), Johan Bylund (Author), Anders Lindén (Author)
• Format: Book
• Published: Karger Publishers, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is incomplete mechanistic understanding of the mobilization of neutrophils in the systemic and local compartment in smokers with chronic obstructive pulmonary disease (COPD). In this pilot study, we characterized how the adhesion molecules CD11b and CD62L, surface markers indicative of priming...