Inhibition of inflammatory liver injury by the HMGB1-A box through HMGB1/TLR-4/NF-κB signaling in an acute liver failure mouse model

Inhibition of inflammatory liver injury by the HMGB1-A box through HMGB1/TLR-4/NF-κB signaling in an acute liver failure mouse model

We aimed to investigate the preventive effect of high mobility group box 1 (HMGB1)-A box and the mechanism by which it alleviates inflammatory injury in acute liver failure (ALF) by inhibiting the extracellular release of HMGB1. BALB/c mice were intraperitoneally (i.p.) administered LPS/D-GalN to es...

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Main Authors: Lidan Luo (Author), Shuai Wang (Author), Bohao Chen (Author), Mei Zhong (Author), Ruili Du (Author), ChunShan Wei (Author), Furong Huang (Author), Xinhui Kou (Author), Yufeng Xing (Author), Guangdong Tong (Author)
Format: Book
Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
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