Physiologically based absorption modeling to predict the bioequivalence of two apixaban formulations

• Main Authors: Ting Luo (Author), Lu Wang (Author), Zourong Ruan (Author), Honggang Lou (Author), Dandan Yang (Author), Zhiyang Wang (Author), Pengfei Zhao (Author), Bo Jiang (Author)
• Format: Book
• Published: Wiley, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The equivalence of absorption rates and extents between generic drugs and their reference formulations is crucial for ensuring therapeutic comparability. Bioequivalence (BE) studies are widely utilized and play a pivotal role in substantiating the approval and promotional efforts for generi...