Suppressing adipocyte inflammation promotes insulin resistance in mice

• Main Authors: Qingzhang Zhu (Author), Yu A. An (Author), Min Kim (Author), Zhuzhen Zhang (Author), Shangang Zhao (Author), Yi Zhu (Author), Ingrid Wernstedt Asterholm (Author), Christine M. Kusminski (Author), Philipp E. Scherer (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Obesity-induced insulin resistance is closely associated with chronic subclinical inflammation in white adipose tissue. However, the mechanistic involvement of adipocyte-derived inflammation under these disease conditions remains unclear. Our aim was to investigate the relative inflammati...