Redox-sensitive prodrug nanoassemblies based on linoleic acid-modified docetaxel to resist breast cancers

• Main Authors: Meng Li (Author), Liwen Zhao (Author), Tao Zhang (Author), Yue Shu (Author), Zhonggui He (Author), Yan Ma (Author), Dan Liu (Author), Yongjun Wang (Author)
• Formato: Livro
• Publicado em: Elsevier, 2019-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Prodrug nanoassemblies, which can refrain from large excipients, achieve higher drug loading and control drug release, have been placed as the priority in drug delivery system. Reasoning that glutathione (GSH) and reactive oxygen species (ROS) are highly upgraded in tumor tissues which makes them at...