The role and mechanism of NLRP3 inflammasome-mediated astrocyte activation in dehydrocorydaline against CUMS-induced depression

• Main Authors: Yu Fang (Author), Hong Guo (Author), Qiannan Wang (Author), Congcong Liu (Author), Shuyi Ge (Author), Bohua Yan (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Background: Depression is a common and potentially life-threatening mental illness, and currently, there is a lack of effective treatment. It has been reported that dehydrocorydaline (DHC) can inhibit monoamine transporter uptake in depressed CUMS mice, but more possible mechanisms of action remain...