The microRNA Let-7f Induces Senescence and Exacerbates Oxidative Stress in Retinal Pigment Epithelial Cells

• Asıl Yazarlar: Christina Ortiz (Yazar), Houda Tahiri (Yazar), Chun Yang (Yazar), Claudia Gilbert (Yazar), Carl Fortin (Yazar), Pierre Hardy (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2024-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

This study aims to investigate the role of microRNA let-7f in the dysfunction and degeneration of retinal pigment epithelium (RPE) cells through the induction of senescence and oxidative stress. Furthermore, we explore whether let-7f inhibition can protect these cells against sodium iodate (SI)-indu...