Quick and simple LC-MS/MS method for the determination of simvastatin in human plasma: application to pharmacokinetics and bioequivalence studies

A simple, rapid, and sensitive method based on liquid chromatography-tandem mass spectrometry for the quantitative determination of simvastatin in human plasma was developed and validated. After a simple extraction with methyl tert-butyl ether, the analyte and internal standard (lovastatin) were ana...

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Main Authors: Suéllen Cristina Rennó Silva (Author), Gustavo Rodrigues de Rezende (Author), Vanessa Bergamin Boralli (Author)
Format: Book
Published: Universidade de São Paulo, 2014-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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