Copy number variation is highly correlated with differential gene expression: a pan-cancer study

• Main Authors: Xin Shao (Author), Ning Lv (Author), Jie Liao (Author), Jinbo Long (Author), Rui Xue (Author), Ni Ai (Author), Donghang Xu (Author), Xiaohui Fan (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer is a heterogeneous disease with many genetic variations. Lines of evidence have shown copy number variations (CNVs) of certain genes are involved in development and progression of many cancers through the alterations of their gene expression levels on individual or several...