Intranasal Administration of <i>N</i>-acetyl-<span style="font-variant: small-caps">L</span>-cysteine Combined with Cell-Penetrating Peptide-Modified Polymer Nanomicelles as a Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis

• Principais autores: Takumi Kurano (Autor), Takanori Kanazawa (Autor), Shingo Iioka (Autor), Hiromu Kondo (Autor), Yasuhiro Kosuge (Autor), Toyofumi Suzuki (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Intranasal administration is a promising route for direct drug delivery to the brain; its combination with nanocarriers enhances delivery. We have previously shown that intranasal administration combined with PEG-PCL-Tat (a nanocarrier) efficiently delivers drugs to the brain and exhibits excellent...