Facilitating plasmid nuclear delivery by interfering with the selective nuclear pore barrier

• Main Authors: Ihab Azzam (Author), Ivan Liashkovich (Author), Isabelle Luchtefeld (Author), Ivan U. Kouzel (Author), Victor Shahin (Author)
• Format: Bog
• Udgivet: Wiley, 2019-09-01T00:00:00Z.
• Fag: article
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Abstract Nuclear pore complexes (NPCs) are sophisticated transporters assembled from diverse proteins termed nucleoporins (Nups). They control all nucleocytoplasmic transport and form a stringent barrier between the cytosol and the nucleus. While selective receptor‐mediated transport enables translo...